Essential Medical, Inc. has developed two femoral artery closure devices intended to seal femoral punctures following vascular access medical procedures requiring a cardiac catheterization. MANTA is designed to close large bore punctures (10-25F) following procedures such as transcatheter aortic valve replacement (TAVR), abdominal aortic aneurysm repair (AAA/PVAR), and balloon aortic valvuloplasty (BAV). These procedures are one of the fastest growing segments within interventional cardiology. X-Seal is designed for smaller bore arterial punctures following more common procedures such as angiography, angioplasty, and stenting, which constitute the large majority of patients treated via arterial catheterization. Both MANTA and X-Seal are ‘anchor/plug’ sealing technologies employing common absorbable biomaterials, with the advantage of x-ray visibility and improved deployment control. MANTA employs novel deployment methods never before utilized for puncture closure.