Third Eye Diagnostics, Inc. is developing the Cerepress™, a first-of-its-kind non-invasive intracranial pressure monitor that gathers information from the patient’s eye. The technology is based on one issued patent, one pending patent, and two applications in progress on methods and apparatus that correlate ICP with measurements taken from the blood vessels within the eye. The Cerepress™ measures blood pressure in the eye’s central retinal vein (CRV) which highly correlates to intracranial pressure.
To obtain CRV pressure, 3ED has developed a novel apparatus that simultaneously records images of the CRV and measures intraocular pressure (IOP) while pressure in the eye is increased. A medical technician aligns the system by easily centering the field of view to patient’s pupil eye. The system then contacts the patient’s cornea and simultaneously collects images of the cornea and the retinal fundus. The contact force increases the IOP and momentarily compresses the CRV. At the instant of complete CRV compression, the Cerepress™ records the eye pressure, which is equivalent to CRV pressure. CRV pressure is a known to be a good correlate to ICP.
The output of the device is a single point reading of intracranial pressure in units of mmHg, which can be performed serially as often as necessary.